GenderBiology.net

Animal Findings Suggest That Gender May Influence Bisphenol A Chemical Exposure Risks For Humans

SOURCE:  Medical News Today

DATE: February 14, 2013

EXCERPT: "A series of experiments ... studied the effects of prenatal exposure to bisphenol A (BPA) on later reproductive-associated behaviors using a socially and genetically monogamous rodent, the California mouse, which may better mirror most human societies than other rodents."  more

RELATED PUBMED LINK:

Williams SA, Jasarevic E, Vandas GM, Warzak DA, Geary DC, Ellersieck MR, Roberts RM, Rosenfeld CS.  Effects of Developmental Bisphenol A Exposure on Reproductive-Related Behaviors in California Mice (Peromyscus californicus): A Monogamous Animal Model.  PLoS One. 2013;8(2):e55698.

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Women Should Be Included In Reproductive Health Research

SOURCE:  Medical News Today

DATE: October 18, 2012

EXCERPT: "A team of Northwestern University scientists will meet with Environmental Protection Agency (EPA) administrators in Washington D.C. Oct. 18 to advocate for important changes in the agency's guidelines for reproductive health research. ...  The Northwestern team will ask the EPA to expand the definition of reproductive health beyond pregnancy to include the lifespan of an individual. ... The Northwestern scientists also will request that all EPA-sponsored research require appropriate testing in both sexes. Currently many toxicity studies are only conducted in male animal models with the assumption that females are affected the same way, but that isn't necessarily true."  more

BPA Risks To Pregnant Women, Newborn Boys Through Thyroid Hormone Changes

SOURCE:  Medical News Today

DATE: October 7, 2012

EXCERPTS: "Bisphenol A (BPA), an estrogen-like compound that has drawn increased scrutiny in recent years, has been linked to changes in thyroid hormone levels in pregnant women and newborn boys, according to a new study

...

For newborn boys, each doubling of BPA levels linked to a 9.9 percent decrease in thyroid stimulating hormone (TSH), indicating a hyperthyroid effect. ... "In addition, studies suggest that small changes in thyroid level, even if they're within normal limits, may still have a cognitive effect."

...

It was not clear why an association was not found among newborn girls, but animal studies may provide some clues. One study in neonatal rats found a similar hyperthyroidic effect in males, but not females. Another study found that female rats had higher levels of an enzyme important in metabolizing BPA when compared with their male counterparts. Whether that same relationship holds true for humans is not yet clear."  more

RELATED PUBMED LINK:

Chevrier J, Gunier RB, Bradman A, Holland NT, Calafat AM, Eskenazi B, Harley KG. Maternal Urinary Bisphenol A during Pregnancy and Maternal and Neonatal Thyroid Function in the CHAMACOS Study. Environ Health Perspect. 2012 Sep 25.


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Risk Of Diabetes In Women May Be Increased By Chemicals In Personal Care Products

SOURCE:  Medical News Today

DATE: July 16, 2012

EXCERPT: "A study lead by researchers from Brigham and Women's Hospital (BWH) shows an association between increased concentrations of phthalates in the body and an increased risk of diabetes in women. Phthalates are endocrine disrupting chemicals that are commonly found in personal care products such as moisturizers, nail polishes, soaps, hair sprays and perfumes. They are also used in adhesives, electronics, toys and a variety of other products. This finding is published online in Environmental Health Perspectives."  more

RELATED PUBMED LINK:

James-Todd T, Stahlhut R, Meeker JD, Powell SG, Hauser R, Huang T, Rich-Edwards J. Urinary Phthalate Metabolite Concentrations and Diabetes among Women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Environ Health Perspect. 2012 Jul 13. [Epub ahead of print]


*Note: if you do not have access to this journal, contact your local librarian for assistance in accessing this article through library resources.

Pesticides Linked to RA, Lupus Risk

SOURCE: MedPage Today

DATE: February 01, 2011

EXCERPT: "Women's risk of developing autoimmune rheumatic disease increases incrementally according to the frequency and duration of their exposure to insecticides, a large observational study suggested."   more

RELATED PUBMED LINKS:

Primary Source:

Parks CG, Walitt BT, Pettinger M, Chen JC, de Roos AJ, Hunt J, Sarto G, Howard BV. Insecticide use and risk of rheumatoid arthritis and systemic lupus erythematosus in the Women's Health Initiative Observational Study. Arthritis Care Res (Hoboken). 2011 Feb;63(2):184-94.

Additional Source:

Costenbader K, Laden F. What do pesticides, farming, and dose effects have to do with the risk of developing connective tissue disease? Arthritis Care Res (Hoboken). 2011 Feb;63(2):175-7.

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BPA Linked to Hormonal Effects in Men

SOURCE:  MedPage Today

DATE:  August 25, 2010

EXCERPT: "Increased exposure to a chemical common to food and drink packaging predicted higher testosterone levels in men, suggesting the chemical bisphenol A (BPA) effects endocrine changes in men, data from a cohort study showed.  ....  BPA excretion was not associated with other serum parameters in men and had no associations with serum outcomes in women."   more

RELATED PUBMED LINK:

Galloway T, Cipelli R, Guralnick J, Ferrucci L, Bandinelli S, Corsi AM, Money C, McCormack P, Melzer D. Daily Bisphenol  Excretion and Associations with Sex Hormone Concentrations: Results from the InCHIANTI Adult Population Study.  Environ Health Perspect. 2010 Aug 25.


*Note: if you do not have access to this journal, contact your local librarian for assistance in accessing this article through library resources.

Inhaling Diabetes? Study Suggests Link Between Air Pollution and Type 2 Diabetes in Women

SOURCE:  Newswise

DATE:  May 24, 2010

EXCERPT:  "Traffic-related air pollution, known to raise the risk for cardiovascular disease, may also increase the risk of developing type 2 diabetes in women. Low-grade inflammation may contribute to the higher incidence of type 2 diabetes in women exposed to air pollution, according to German researchers."  more

RELATED PUBMED LINK:

Krämer U, Herder C, Sugiri D, Strassburger K, Schikowski T, Ranft U, Rathmann W. Traffic-related Air Pollution and Incident Type 2 Diabetes: Results from the SALIA Cohort Study. Environ Health Perspect. 2010 May 11.


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Exposure to Three Classes of Common Chemicals May Affect Female Development

SOURCE:  Newswise

DATE:  April 5, 2010

EXCERPT: "Researchers at Mount Sinai School of Medicine have found that exposure to three common chemical classes—phenols, phthalates and phytoestrogens—in young girls may disrupt the timing of pubertal development, and put girls at risk for health complications later in life."    more

RELATED PUBMED LINK:

Wolff MS, Teitelbaum SL, Pinney SM, Windham G, Liao L, Biro F, Kushi LH, Erdmann C, Hiatt RA, Rybak ME, Calafat AM; Breast Cancer and Environment Research Centers. Investigation of Relationships between Urinary Biomarkers of Phytoestrogens, Phthalates, and Phenols and Pubertal Stages in Girls. Environ Health Perspect. 2010 Mar 22.

*Note: if you do not have access to this journal, contact your local librarian for assistance in accessing this article through library resources.

Exposure To Insecticide May Play Role In Obesity Epidemic Among Some Women

SOURCE: Medical News Today

DATE:  March 21, 2009

EXCERPT: "Prenatal exposure to an insecticide commonly used up until the 1970s may play a role in the obesity epidemic in women, ...."   more

RELATED PUBMED LINK:

Karmaus W, Osuch JR, Eneli I, Mudd LM, Zhang J, Mikucki D, Haan P, Davis S. Maternal levels of dichlorodiphenyl-dichloroethylene (DDE) may increase weight and body mass index in adult female offspring. Occup Environ Med. 2009 Mar;66(3):143-9. Epub 2008 Dec 5.

Recovery From Pneumonia After Ozone Exposure May Be Affected By Gender

SOURCE:  Medical News Today

DATE:  June 28, 2007

EXCERPT:  "Does air pollution have a bigger effect on the immune system of females than males? It did among mice exposed to ozone -- a major component in air pollution that is known to negatively affect lung function -- and then infected with pneumonia, as significantly more females died from the infection than males. "   more

RELATED PUBMED LINK:

Mikerov AN, Haque R, Gan X, Guo X, Phelps DS, Floros J. Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences. Respir Res. 2008 Dec 4;9:77.