GenderBiology.net

Lower Antioxidant Level Might Explain Higher Skin-Cancer Rate In Males

SOURCE: Medical News Today

DATE:  December 3, 2011

EXCERPT: "Men are three times more likely than women to develop a common form of skin cancer but medical science doesn't know why. A new study may provide part of the answer."   more

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Sullivan NJ, Tober KL, Burns EM, Schick JS, Riggenbach JA, Mace TA, Bill MA, Young GS, Oberyszyn TM, Lesinski GB. UV Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1(+)CD11b(+) Myeloid Cell Expansion. J Invest Dermatol. 2011 Oct 27. doi: 10.1038/jid.2011.329.


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Vitamin D Unrelated to Mortality Risk in Most Women

SOURCE: MedPage Today

DATE:   November 1, 2011

EXCERPT: "Increased risks for all-cause mortality and death from cancer and cardiovascular disease associated with low vitamin D levels registered only as weak, nonsignificant trends in a large prospective study, researchers said."   more

RELATED PUBMED LINK:

Eaton CB, Young A, Allison MA, Robinson J, Martin LW, Kuller LH, Johnson KC, Curb JD, Van Horn L, McTiernan A, Liu S, Manson JE. Prospective association of vitamin D concentrations with mortality in postmenopausal women: results from the Women's Health Initiative (WHI). Am J Clin Nutr. 2011 Dec;94(6):1471-8. Epub 2011 Oct 26.

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Cigarette Smoking Implicated in Half of Bladder Cancers in Women

SOURCE: NIH News

DATE:  August 16, 2011

EXCERPT: "Current cigarette smokers have a higher risk of bladder cancer than previously reported, and the risk in women is now comparable to that in men, according to a study  ...."   more

RELATED PUBMED LINK:

Freedman ND, Silverman DT, Hollenbeck AR, Schatzkin A, Abnet CC. Association between smoking and risk of bladder cancer among men and women. JAMA. 2011 Aug 17;306(7):737-45.

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No Lung Cancer Hazard With Estrogen

SOURCE:  MedPage Today

DATE:  August 14, 2010

EXCERPT: "Unopposed estrogen does not increase lung cancer incidence or mortality in postmenopausal women, according to data from the Women's Health Initiative (WHI)."   more

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Li CI, Chlebowski RT, Freiberg M, Johnson KC, Kuller L, Lane D, Lessin L, O'Sullivan MJ, Wactawski-Wende J, Yasmeen S, Prentice R. Alcohol Consumption and Risk of Postmenopausal Breast Cancer by Subtype: the Women's Health Initiative Observational Study. J Natl Cancer Inst. 2010 Aug 23.

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Women Benefit More from NSCLC Agent

SOURCE:  MedPage Today

DATE:  June 9, 2010

EXCERPT:  "The targeted agent erlotinib (Tarceva) prolonged survival by 26% in older women with advanced non-small cell lung cancer but did not benefit men with the disease, ..."  more

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Presented by Siow Ming Lee, MD, PhD, of the University College London Cancer Institute at the American Society of Clinical Oncology Annual Meeting held 4-8 June 2010 at Chicago, IL. 

Out of the Shadows: Women and Lung Cancer

SOURCE:  Newswise

DATE:  April 26, 2010

EXCERPT: "Out of the Shadows: Women and Lung Cancer, a groundbreaking report released today by the Mary Horrigan Connors Center for Women’s Health at Brigham and Women’s Hospital, a teaching affiliate of Harvard Medical School, is a call to action on women’s largest cancer challenge: lung cancer."   more

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REPORT:  Out of the Shadows: Women and Lung Cancer 

Gender Differences In Lung Cancer Incidence: Smoke Exposure Alters Gene Expression And Estrogen Metabolism In The Lungs Of Mice

SOURCE:  Medical News Today

DATE: April 29, 2010

EXCERPT: "Lung cancer rates are increasing substantially in women, particularly in non-smoking women, with no known reason for the increase. Now researchers at Fox Chase Cancer Center may have uncovered a critical piece in the puzzle.  ...  team hypothesizes that estrogen metabolism may contribute to lung cancer in non-smoking women as well."   more

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Presented by Margie Clapper at the 101st Annual meeting of the American Association for Cancer Research, 17-21 April 2010, Washington, D.C.

Radiation Treatment: Age, Gender Can Affect Risk

SOURCE:  Medical News Today

DATE:  March 18, 2010

EXCERPT:  " Most current estimates of bone marrow radiation dose are obtained from two-dimensional images acquired from seven skeletal sites in a 44-year-old adult male during the late 1960s, Bolch said. UF's current work seeks to replace these widely used estimates from the University of Leeds by using three-dimensional imaging and extending the work to the pediatric and prenatal skeleton. The work will illustrate how bone marrow radiation dose can vary with patient size, whether a patient has osteoporosis, and marrow health."Wes Bolch is doing research that will give clinicians the tools to reduce the level of patients' radiation exposure. It's very important work," said George Xu, Ph.D, a professor in the department of mechanical, aerospace and nuclear engineering at Rensselaer Polytechnic Institute in Troy, N.Y.   ....   The models are being created at a time when the medical community is sounding the alarm about the potential for harm from excessive radiation exposure. According to the National Council on Radiation Protection and Measurements, the average annual radiation exposure in the United States increased about 75 percent between 1982 and 2006. During that time, the proportion of exposure due to medical interventions rose from 15 percent to 48 percent."   more

RELATED PUBMED LINK:

Dimbylow P, Bolch W, Lee C. SAR calculations from 20 MHz to 6 GHz in the University of Florida newborn voxel phantom and their implications for dosimetry. Phys Med Biol. 2010 Mar 7;55(5):1519-30.

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Mayo Clinic Study on How to Minimize Radiation Risks of Angioplasty Shows Highest Doses in Men, Large Body Mass, Complex Cases

SOURCE: Mayo Clinic

DATE:  March 15, 2010

EXCERPT: "Body size, gender and the complexity of heart disease significantly influence how much cumulative radiation skin dose that patients receive during percutaneous coronary intervention (PCI) therapy, also known as angioplasty, according to a new Mayo Clinic study. The study was undertaken as a quality control initiative to reduce the potential radiation risks of cancer to patients and PCI operators."   more

Occupational Sunlight Exposure And Kidney Cancer Risk In Men

SOURCE:  Medical News Today

DATE:  March 8, 2010

EXCERPT: "According to a new study, men employed in occupations with potential exposure to high levels of sunlight have a reduced risk of kidney cancer compared with men who were less likely to be exposed to sunlight at work. The study did not find an association between occupational sunlight exposure and kidney cancer risk in women."   more

RELATED PUBMED LINK:

Karami S, Boffetta P, Stewart P, Rothman N, Hunting KL, Dosemeci M, Berndt SI, Brennan P, Chow WH, Moore LE. Occupational sunlight exposure and risk of renal cell carcinoma. Cancer. 2010 Mar 8.


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