Could Hormones Explain Gender Differences In Neurological Disease?

SOURCE:  Medical News Today

DATE:  June 17, 2009

EXCERPT:  "Neurological diseases including Parkinson's, Tourette's, attention deficit hyperactivity disorder (ADHD), Alzheimer's, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT). Research published recently in the open access journal BMC Neuroscience suggests that a number of estrogens acting through their receptors affect the DAT, which may explain trends in timing of women's susceptibility to these diseases."   more

RELATED PUBMED LINK:

Alyea RA, Watson CS. Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux. BMC Neurosci. 2009 Jun 16;10(1):59. Free full text