Low And High Levels Of Hormone In Men With Heart Failure Associated With Increased Risk Of Death

SOURCE:  Medical News Today

DATE:  May 15, 2009

EXCERPT:  "Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, .... Estrogens have numerous biological effects in men and have a complex effect on the normal cardiovascular system, including cardioprotective effects, which may explain the link between low estradiol concentrations and an increased risk of cardiovascular events in men, according to background information in the article." more

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Jankowska EA, Rozentryt P, Ponikowska B, Hartmann O, Kustrzycka-Kratochwil D, Reczuch K, Nowak J, Borodulin-Nadzieja L, Polonski L, Banasiak W, Poole-Wilson PA, Anker SD, Ponikowski P. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901.