GenderBiology.net

Genomic Health Study Shows Breast Cancers In Men Display Very Similar Gene Signatures To Those In Women

SOURCE:  Medical News Today

DATE:  May 30, 2009

EXCERPT: " ....  breast cancer in men displays similar gene signatures to female breast cancer."    more

RELATED LINKS:

Poster presentation on Monday, June 1 (1:00 - 5:00 p.m. ET)
S. Shak, G. Palmer, F. L. Baehner, C. Millward, D. Watson, G. W. Sledge; Genomic Health, Redwood City, CA; Indiana University School of Medicine, Indianapolis, IN. Molecular characterization of male breast cancer by standardized quantitative RT-PCR analysis: First large genomic study of 347 male breast cancers compared to 82,434 female breast cancers.Poster presentation.   American Society of Clinical Oncology (ASCO) Annual Meeting, 2009 May 29- June 2,  Orlando, FL. Abstract 549.

See also J Clin Oncol 27:15s, 2009 (suppl; abstr 549)

Perimenopause Associated with Cognitive Decline

SOURCE:  MedPage Today

DATE:  May 27, 2009

EXCERPT:  "Women lose their intellectual edge in perimenopause, but regain it in the later phases of menopause, researchers say. ... The researchers noted that about 60% of women report memory problems during the transition into menopause. However, the issue of 'brain fog' during the various phases of menopause had not been well investigated.   more

RELATED PUBMED LINK:

Greendale GA, Huang MH, Wight RG, Seeman T, Luetters C, Avis NE, Johnston J, Karlamangla AS. Effects of the menopause transition and hormone use on cognitive performance in midlife women. Neurology. 2009 May 26;72(21):1850-7.

RELATED LINK:

Menopause Transition May Cause Trouble Learning

Low Vitamin D May Slow Cognition in Older Men

SOURCE:  MedPage Today

DATE:  May 21, 2009

EXCERPT:  "Low levels of 25-hydroxyvitamin D [vitamin d] may be linked to slower information processing in men of middle age and older, researchers say."  more

RELATED PUBMED LINK:

Lee DM, Tajar A, Ulubaev A, Pendleton N, O'Neill TW, O'Connor DB, Bartfai G, Boonen S, Bouillon R, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Silman AJ, Vanderschueren D, Wu FC. Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men. J Neurol Neurosurg Psychiatry. 2009 May 21. [Epub ahead of print]

UCLA Discovery May Explain Why Autism Strikes Boys Four Times More Than Girls

SOURCE:  Medical News Today

DATE:  May 20, 2009

EXCERPT: "UCLA scientists have discovered a variant of a gene called CACNA1G that may increase a child's risk of developing autism, particularly in boys."   more

RELATED PUBMED LINK:

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Strom SP, Stone JL, Ten Bosch JR, Merriman B, Cantor RM, Geschwind DH, Nelson SF. The journal Molecular Psychiatry publishes the findings in its May 19 advance online edition. High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene. Mol Psychiatry. 2009 May 19. [Epub ahead of print]

Women With Chest Pain Less Likely Then Men To Get Proper Treatment From Paramedics

SOURCE:  Medical News Today

DATE: May 16, 2009

EXCERPT: "Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital, ..." more

RELATED LINKS:

Society for Academic Emergency Medicine Annual Meeting, 14-17 May 2009, New Orleans. [Results presented by Zachary Mesiel, May 15.]

Low And High Levels Of Hormone In Men With Heart Failure Associated With Increased Risk Of Death

SOURCE:  Medical News Today

DATE:  May 15, 2009

EXCERPT:  "Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, .... Estrogens have numerous biological effects in men and have a complex effect on the normal cardiovascular system, including cardioprotective effects, which may explain the link between low estradiol concentrations and an increased risk of cardiovascular events in men, according to background information in the article." more

RELATED PUBMED LINK:

Jankowska EA, Rozentryt P, Ponikowska B, Hartmann O, Kustrzycka-Kratochwil D, Reczuch K, Nowak J, Borodulin-Nadzieja L, Polonski L, Banasiak W, Poole-Wilson PA, Anker SD, Ponikowski P. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901.

Women Face Higher Burden Than Men From Rising Health Care Costs, Study Finds

SOURCE:  Medical News Today

DATE: May 13, 2009

EXCERPT:  "About 70% of working-age women in the U.S., or 63.8 million women, are uninsured, underinsured, have medical debt or have not sought needed care because of high costs, .... Fifty-nine percent of working-age men, or about 51.9 million men, fall into the same categories." more

RELATED LINKS:

Rustgi S.D., Doty M.M., & Collins S.R. Women at Risk: Why Many Women Are Forgoing Needed Health Care, Commenwealth Fund Issue Brief. 11 May 2009, Vol. 52

Why Women Aren't Getting the Health Care They Need (podcast), Commonwealth Fund Report

Commonwealth Fund

Women With Hard To Diagnose Chest Pain Symptoms At Higher Risk For Cardiovascular Events

SOURCE:  Medical News Today

DATE: May 12, 2009

EXCERPT:  "Many physicians are presented with the following scenario: a woman comes into the office complaining of chest pain, undergoes a stress test to evaluate the chest pain, and the stress test results suggest coronary artery disease, a condition in which plaque builds up inside the coronary arteries. She is then referred for an angiogram to look at the coronary arteries and despite her symptoms and the abnormal stress test, she is told that the tests didn't find anything of clinical significance and is sent home without treatment. However, a new study may change this by offering greater insight into the causes behind chest pain in women and how it manifests differently in women than it does in men. The study ... shows that women with chest pain but without coronary artery disease are at an elevated risk for cardiovascular events such as heart attack or stroke."  more

RELATED PUBMED LINK:

Gulati M, Cooper-DeHoff RM, McClure C, Johnson BD, Shaw LJ, Handberg EM, Zineh I, Kelsey SF, Arnsdorf MF, Black HR, Pepine CJ, Merz CN. Adverse cardiovascular outcomes in women with nonobstructive coronary artery disease: a report from the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project. Arch Intern 2009 May 11;169(9):843-50.

Estradiol Extremes Increase Mortality in Men with CHF

SOURCE:  MedPage Today

DATE:  May 12, 2009

EXCERPT:  "Men with chronic heart failure have a significantly increased mortality risk if their estradiol levels are at the extreme ends of the concentration range, ....  Men with low estradiol levels had as much as a 50% lower survival compared with men who had mid-range levels of the female hormone, ..."  more

RELATED PUBMED LINK:

Jankowska EA, Rozentryt P, Ponikowska B, Hartmann O, Kustrzycka-Kratochwil D, Reczuch K, Nowak J, Borodulin-Nadzieja L, Polonski L, Banasiak W, Poole-Wilson PA, Anker SD, Ponikowski P. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901.

Women Who Follow Blood Pressure-Lowering Diet Have Reduced Risk For Heart Failure

SOURCE:  Medical News Today

DATE: May 12, 2009

EXCERPT: "A diet designed to prevent and treat high blood pressure also may be associated with a lower risk of heart failure among women,... " more

RELATED PUBMED LINK:

Levitan EB, Wolk A, Mittleman MA. Consistency with the DASH diet and incidence of heart failure. Arch Intern Med. 2009 May 11;169(9):851-7.