SOURCE: Medical News Today
DATE: January 22, 2008
EXCERPT: "An international consortium of scientists has identified multiple genes that are linked to systemic lupus erythematosus, a devastating autoimmune disease that affects between 1 million and 2 million Americans. ..... Systemic lupus can involve the joints, kidneys, heart, lungs, brain and blood. The disease .... affects women nine times more frequently than men." more
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Nath SK, Han S, Kim-Howard X, Kelly JA, Viswanathan P, Gilkeson GS, Chen W, Zhu C, McEver RP, Kimberly RP, Alarcón-Riquelme ME, Vyse TJ, Li QZ, Wakeland EK, Merrill JT, James JA, Kaufman KM, Guthridge JM, Harley JB. A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet. 2008 Feb;40(2):152-4. Epub 2008 Jan 20.
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